CVE-2021-45382: in the CISA KEV catalogue
D-Link Multiple Routers Remote Code Execution Vulnerability. CISA added CVE-2021-45382 to the Known Exploited Vulnerabilities catalogue on 2022-04-04 with a default due date of 2022-04-25. Known ransomware campaign use: Unknown. Forensic triage flag: No.
A remote code execution vulnerability exists in all series H/W revisions routers via the DDNS function in ncc2 binary file. (CISA description)
- Vendor / product
- D-Link Multiple Routers
- CWE
- CWE-78
- CISA required action
- The impacted product is end-of-life and should be disconnected if still in use.
- EPSS
- 98%, percentile 99 (scored 2026-11-03)
EPSS puts about 98 in 100 odds (98%) on exploitation activity being observed in the next 30 days. Its score is higher than or equal to that of 99% of scored CVEs. This is a model estimate about exploitation anywhere, not about your environment.
Vendor and reference links (from CISA)
Your own deadline under CISA BOD 26-04 depends on exposure, automatability and technical impact: work it out with the BOD 26-04 calculator.
Frequently asked questions
Is CVE-2021-45382 in the CISA KEV catalogue?
Yes. CISA added CVE-2021-45382 (D-Link Multiple Routers Remote Code Execution Vulnerability) to the Known Exploited Vulnerabilities catalogue on 2022-04-04. CISA's default due date for it is 2022-04-25.
Is CVE-2021-45382 used in ransomware attacks?
CISA marks known ransomware campaign use as Unknown for CVE-2021-45382. That means CISA lacks confirmation, not that ransomware groups do not use it.
What should I do about CVE-2021-45382?
CISA's required action: The impacted product is end-of-life and should be disconnected if still in use.
Sources
- CISA, Known Exploited Vulnerabilities Catalog (accessed 2026-11-03)
- FIRST, Exploit Prediction Scoring System (EPSS) (EPSS by FIRST; scores generated by Empirical Security)
- NVD record for CVE-2021-45382